Pre-Implantation Genetic Screening (PGS)

Genetic screening

PGS (pre-implantation genetic screening) is a technique used during IVF treatment to screen embryos for any abnormalities in their genetic material (chromosomes).

How does it work?

In a PGS procedure, the embryologist removes some cells from each embryo by biopsy.  At Reproductive Health Group this is done at the blastocyst (5 day) stage of the embryo’s development as occasionally chromosomally abnormal embryos can develop quite normally up to the first five days. The cells are checked in a genetics laboratory to ensure that the correct number of chromosomes is present. Embryos with the correct number of chromosomes  are given priority for transfer back into the patient’s womb.

Why is PGS used

Recent research has suggested that IVF success rates may be improved if embryos are first screened for chromosomal abnormalities and embryos with the correct number of chromosomes transferred back. Most abnormal embryos would either fail to implant in the womb or miscarry during pregnancy.

It is potentially suitable for anyone undergoing IVF treatment but may be of particular benefit for women over the age of 35, in cases where there have been several failed cycles of IVF already (recurrent implantation failure) or recurrent  miscarriages, where there is a known family history of chromosomal problems or the male partner’s sperm has been identified as containing a high number of chromosomal abnormalities.

Reproductive Health Group also work with an independent genetic counsellor who is available to provide additional support to patients considering undergoing IVF treatment with PGS.

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You can request an appointment here or call our patient services team now on 01925 202180.

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